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KMID : 0859320080260010010
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Journal of the Korean Society for Therapeutic Radiology and Oncology
2008 Volume.26 No. 1 p.10 ~ p.16
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A Comparison of Clinical Outcomes for Breast-conserving Treatment and Mastectomy for Early Breast Cancer
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Noh Jae-Myoung
Nam Seok-Jin
Huh Seung-Jae
Yang Jung-Hyun
Kim Jung-Han
Im Young-Hyuck
Park Won
Ahn Jin-Seok
Choi Doo-Ho
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Abstract
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Purpose: To compare the treatment outcomes and to analyze prognostic factors between the use of a breast-conserving treatment (BCT) and a mastectomy for early stage breast cancer.
Materials and Methods: We retrospectively reviewed 1,200 patients with pathological stage T1-2N0 breast cancer who received surgery between September 1994 and December 2002 at Samsung Medical Center. We compared the patient characteristics and treatment outcomes between the two treatment groups.
Results: Among the 1,174 eligible patients, 601 (51.2%) patients received a BCT and the remaining 573 (48.8%) patients received a mastectomy. The mastectomy group of patients had significantly more cases with a larger tumor size, multicentricity, extensive intraductal component, and estrogen- and progesterone- receptor negativity. The ten-year overall survival rates (OS) of the BCT and mastectomy groups were 91.96% and 91.01%, respectively (p=0.1274). The ten-year disease-free survival rates (DFS) were 80.48% for the BCT group of patients and 84.95% for the mastectomy group of patients, respectively (p=0.8795).
Conclusion: Our study shows some differences in patient characteristics between the two treatment groups.
However, these differences did not result in significant survival differences.
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KEYWORD
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Breastcancer, Breast-conservingsurgery, Mastectomy
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